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Fetal cardiac malformations and their impact once a child reaches adulthood

The TRIVIA study focuses on one specific malformation, the tetralogy of Fallot.

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The Foundation of Stars has the privilege of working with researchers from all fields of expertise. In the coming months, we will share with you research projects on different axes of pediatric research. Thus you will discover a multitude of well-popularized scientific advances.

To celebrate February, which is Heart Month, we’ll be unveiling information on pediatric cardiology research and some of the most promising and exciting projects currently underway.

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While cardiac malformations are frequent, there are several hundred different types of them, each one rare. Improving the health of children thus afflicted calls for gathering information on numerous patients. Doing this will require the cooperation of as many research centres as possible and the creation of groups representative of the various malformations. The TRIVIA study focuses on one specific malformation, the tetralogy of Fallot. Researchers tabulated the survival rate of the children involved, along with the number of interventions and hospitalizations required, according to type of malformation and the existence of genetic conditions. This information is key to educating and advising parents faced with the shattering news that their newborn child is afflicted with such a malformation.
This study also allowed for discovering that one type of intervention was more promising than the others. The surgery in question increased the odds of survival while diminishing the number of future surgeries needed. An exciting discovery, to say the least!

**F. Dallaire shares his initial observations of the groups studied. **

This second study aims to monitor patients over several decades to gather large-scale data on the long-term quality of life of children with cardiac malformations. This information on the quality of life of children (including once they become adults) is of the utmost importance. To be able to eventually modify the treatments of these diseases, researchers must show that proposed changes would not only improve the odds of survival but also, the quality of life of patients. Studying the quality of life of children in this matter is a surefire way to improve it.

**F. Dallaire speaks about the challenges associated with his research and the methods adopted to carry out such a vast project. **